Systems Biotechnology Group

Multi- and inter-disciplinarity to the service of enzymes: a chemical vision to biological questions for the implementation of biocatalysts in our everyday life.


The research activity of the Systems Biotechnology group lead by Prof. Manuel Ferrer has been markedly multidisciplinary and has had as a common thread to provide a chemical vision to biological questions, with the ultimate goal of producing basic and technological developments using experimental and theoretical tools. It has been and is a competitive research that is in the interface between the analytical chemistry, the chemical biology, the physical-chemistry, the inorganic chemistry and the organic chemistry, with fields and disciplines such as biology, microbiology, health, medicine, energy, environment and materials, to mention a few.


Our facilities are located at the Institute of Catalysis, in the Autonomous University of Madrid Campus. Enter to take a look!


We are a multidisciplinary team composed on chemists, biochemists, and biologists, in tight collaboration with bioinformatics, to gain a whole perspective of the matters we face. Come and meet us!



A project to develop “Nature-inspired” and “Artificial intelligent-edited” biologics with which to create and implement (micro)plastic-degradation strategies. Both the biologics and the strategies will allow, in a circular economy context, controlling pollution, promoting environmental restoration, and mitigating climate change.


Our goal is the development and implementation of bioremediation/revitalization strategies of targeted EU contaminated sites. We will use predictive microbial interaction models in the microbiome of the real places, to remove >90% of the main contaminants and improve their biodiversity status.


MetaMorph will strive to develop a high-tech platform to perform the MetaMorphosis of enzymes  into a new generation of artificial enzyme designs and BioHybrid catalysts with innovative structures and functionalities.


To really get to enzyme implementation in greener industry, we need to be able to accurately predict enzyme parameters from a protein sequence. This project will develop a technology that will help to recover the precise enzymes from the ever-increasing amount of sequenced data.


Our purpose is to make your textiles, detergents and cosmetics greener than ever. For that, a high-tech platform will use big biodata mining of databases and bioresources, and disruptive machine-learning, amongst others, to develop enzymes to be included in the production of these goods and any others of interest.

Upcoming Events

The “Thermophiles” Conference is coming!

August 29-September 2 2023

The 16th “Thermophiles” International Conference (Bangor University, North Wales, UK) engages various fields of research on thermophilic microorganisms, from ecology, phylogeny, genomics, metagenomics, molecular biology, physiology, astrobiology to biotechnology and other areas of applied microbiology. We hope this conference provides an inspiring and inclusive atmosphere with an excellent opportunity for PhD students and early carriers scientists to meet and interact with experts from worldwide. Join us!


Webinar Enzymes in Europe, what's new?

9 October 2023

The French cluster Bioeconomy forchange  (formerly Pôle IAR) organizes this webinar with the objective of presenting European projects dealing with enzymes, and they selected us as speakers! This event pretends to show trends on enzymatic technologies and to open European entities working on this topic to the cluster’s network. Prof. Manuel Ferrer will talk about FuturEnzyme’s objectives and developments, together with 4 more European projects’ representatives. Interested? Register here!

FuturEnzyme's 30-month Executive Committee meeting

November 2023

Every 6 months, FuturEnzyme’s Executive Committee (composed of the workpackage leaders and the coordinator) gathers to discuss together the advances, news and next steps of the project. These meetings take place online, so we can reduce our carbon footprint. Visit the project’s website to learn more about how we contribute to bioeconomy, circular economy, and fight climate change by applying enzymes to every-day consumer products, such as the clothes you wear, the detergents you wash them with, and the cosmetics that make your skin glow!